Platinum-Based Drugs in Cancer Therapy PDF Download


Download Platinum-Based Drugsin Cancer Therapy pdf by Lloyd R. Kelland and Nicholas P. Farrell

BOOKS NAME: Platinum-BasedDrugs in Cancer Therapy

Books SERIES: Pharmacology

language : English

PUBLISH: December 8, 2010

ISBN-10 / ASIN: 1617370916

Page: 360 pages

File type: PDF

File size: 105,70 MB

Publisher: Humana Press

Author: Lloyd R. Kelland and Nicholas P. Farrell



Leading international experts comprehensively review all aspects of platinum anticancer drugsand their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinumdrugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs.



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